2018 / 01

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DOI: 10.24075/brsmu.2018.012

ORIGINAL RESEARCH

Assessment of perioperative prophylaxis of infectious complications in post-op patients

Morozova TE, Lukina MV, Andrushishina TB, Chukina MA
About authors

Department of Clinical Pharmacology and Propedeutics of Internal Diseases, Faculty of General Medicine,
I.M. Sechenov First Moscow State Medical University, Moscow

Correspondence should be addressed : Maria V. Lukina
Bolshaya Pirogovskaya 2, str. 4, k. 106, Moscow, 119435; ur.xednay@0102kul-iram

About paper

Acknowledgements: the authors thank Oleg Babenko of Clinical Hospital No.1 of I.M. Sechenov First Moscow State Medical University for granting access to Hospital’s archived medical records.

Received: 2017-12-29 Accepted: 2018-03-23 Published online: 2018-04-30
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Table 1. Clinical characteristics of patients included in the analysis
Note : * — creatinine levels and clearance rates (Cockcroft-Gault equation) before surgery; ** — creatinine levels and clearance rates (Cockcroft-Gault equation) 24–48 h after surgery
Table 2. Antibacterial agents used in perioperative prophylaxis and inappropriate dosing
Table 3. Duration of perioperative prophylaxis
Table 4. Frequency of adverse reactions depending on PAP duration
Table 5. Associations between clinical and laboratory parameters and the risk of adverse reactions
Table 6.Frequency and type of infectious complications in patients with different types of wound contamination undergoing perioperative prophylaxis
Note: * — infective endocarditis, urinary tract infection, нnosocomial tracheobronchitis, intraabdominal infection
Table 7. Impact of inadequate PAP regimens on hospital statistics