Rustem N. KHAZIPOV
Director for Research,
Institut de Neurobiologie de la Méditerranée – INSERM (INMED) U901 (Marseilles, France)
Lead Researcher at the OpenLab of the Institute of Fundamental Medicine and Biology,
Kazan Federal University (Kazan, Russia)
Areas of expertise:
synaptic transmission, ion channels, neuronal networks, ontogenesis of the nervous system, GABAergic inhibition
Special awards and honors:
Winner of Government of the Russian Federation Grant competition for leading scientists (2011)
At the moment, neurobiology is one of the most interesting areas of research. Its primary task is to understand how the human brain functions — the most complex structure ever created by nature; to understand what lies behind our thoughts, actions and emotions. If we decipher the basic principles of brain work, we will be able to give an accurate materialistic description of what our consciousness and soul are. Moreover, we will know how to treat nervous system disorders, many of which are still a realm of psychiatrists, although they have a material cause. It will be possible to record information stored in our consciousness and create realistic models of a brain of a particular person; we will learn to place consciousness into a world of virtual technologies and to control neural activity in order to treat nervous system pathologies. Our time is unique because we are on the verge of great discoveries, and young researchers who decided to go into neurobiology have a chance to participate in solving these challenging tasks.
- Inácio AR, Nasretdinov A, Lebedeva J, Khazipov R. Sensory feedback synchronizes motor and sensory neuronal networks in the neonatal rat spinal cord. Nat Commun. 2016 Oct 7; 7: 13060. DOI: 10.1038/ncomms13060.
- Akhmetshina D, Nasretdinov A, Zakharov A, Valeeva G, Khazipov R. The Nature of the Sensory Input to the Neonatal Rat Barrel Cortex. J Neurosci. 2016 Sep 21; 36 (38): 9922–32. DOI: 10.1523/JNEUROSCI.1781-16.2016.
- Valeeva G, Tressard T, Mukhtarov M, Baude A, Khazipov R. An Optogenetic Approach for Investigation of Excitatory and Inhibitory Network GABA Actions in Mice Expressing Channelrhodopsin-2 in GABAergic Neurons. J Neurosci. 2016 Jun 1; 36 (22): 5961–73. DOI: 10.1523/JNEUROSCI.3482-15.2016.
- Akhmetshina D, Zakharov A, Vinokurova D, Nasretdinov A, Valeeva G, Khazipov R. The serotonin reuptake inhibitor citalopram suppresses activity in the neonatal rat barrel cortex in vivo. Brain Res Bull. 2016 Jun; 124: 48–54. DOI: 10.1016/j.brainresbull.2016.03.011.
- Lebedeva J, Zakharov A, Ogievetsky E, Minlebaeva A, Kurbanov R, Gerasimova E, Sitdikova G, Khazipov R. Inhibition of Cortical Activity and Apoptosis Caused by Ethanol in Neonatal Rats In Vivo. Cereb Cortex. 2015 Dec 8. pii: bhv293. [Epub ahead of print].
- Khalilov I, Minlebaev M, Mukhtarov M, Khazipov R. Dynamic Changes from Depolarizing to Hyperpolarizing GABAergic Actions during Giant Depolarizing Potentials in the Neonatal Rat Hippocampus. J Neurosci. 2015 Sep 16; 35 (37): 12635–42. DOI: 10.1523/JNEUROSCI.1922-15.2015.
- Sitdikova G, Zakharov A, Janackova S, Gerasimova E, Lebedeva J, Inacio AR, Zaynutdinova D, Minlebaev M, Holmes GL, Khazipov R. Isoflurane suppresses early cortical activity. Ann Clin Transl Neurol. 2014 Jan; 1 (1): 15–26. DOI: 10.1002/acn3.16.
- Mitrukhina O, Suchkov D, Khazipov R, Minlebaev M. Imprecise Whisker Map in the Neonatal Rat Barrel Cortex. Cereb Cortex. 2015 Oct; 25 (10): 3458–67. DOI: 10.1093/cercor/bhu169.
- Minlebaev M, Valeeva G, Tcheremiskine V, Coustillier G, Khazipov R. Cell-attached recordings of responses evoked by photorelease of GABA in the immature cortical neurons. Front Cell Neurosci. 2013 May 31; 7: 83. DOI: 10.3389/fncel.2013.00083.
- Dzhala V, Valeeva G, Glykys J, Khazipov R, Staley K. Traumatic alterations in GABA signaling disrupt hippocampal network activity in the developing brain. J Neurosci. 2012 Mar 21; 32 (12): 4017–31. DOI: 10.1523/JNEUROSCI.5139-11.2012.