ISSN Print 2500–1094    ISSN Online 2542–1204
Bulletin of RSMU


Director of the Institute of Translational Medicine,
Saint Petersburg State University (St. Peresburg, Russia)

Skolkovo Institute of Science and Technology (Moscow, Russia)

CSc (medicine)

Areas of expertise:

neuroscience, experimental pharmacology (studies on schizophrenia, depression, Parkinson’s disease, and attention-deficit hyperactivity disorder in transgenic animal models)

Special awards and honors:

Since 2013 Chair of the Subcommittee for the Dopamine receptors of the Committee on Receptor Nomenclature and Drug Classification of the International Union of Basic and Clinical Pharmacology (IUPHAR), the world’s largest association of pharmacologists

Significant publications in last 5 years

  1. Fox ME, Mikhailova MA, Bass CE, Takmakov P, Gainetdinov RR, Budygin EA, Wightman RM. Cross-hemispheric dopamine projections have functional significance. Proc Natl Acad Sci U S A. 2016;113: 6985–90.
  2. Sukhanov I, Caffino L, Efimova EV, Espinoza S, Sotnikova TD, Cervo L, Fumagalli F, Gainetdinov RRIncreased context-dependent conditioning to amphetamine in mice lacking TAAR1. Pharmacol Res. 2016 Jan; 103: 206–14.
  3. Espinoza S, Lignani G, Caffino L, Maggi S, Sukhanov I, Leo D, Mus L, Emanuele M, Ronzitti G, Harmeier A, Medrihan L, Sotnikova TD, Chieregatti E, Hoener MC, Benfenati F, Tucci V, Fumagalli F, Gainetdinov RRTAAR1 Modulates Cortical Glutamate NMDA Receptor Function. Neuropsychopharmacology 2015 Aug; 40 (9): 2217–27.
  4. Gurevich EV, Premont RT, Gainetdinov RRG protein-coupled receptor kinases: from molecules to diseases. FASEB J. 2015 Feb; 29 (2): 361–4.
  5. Espinoza S, Ghisi V, Emanuele M, Leo D, Sukhanov I, Sotnikova TD, Chieregatti E, Gainetdinov RRPostsynaptic D2 dopamine receptor supersensitivity in the striatum of mice lacking TAAR1. Neuropharmacology. 2015; 93: 308–13.
  6. Beaulieu JM, Espinoza S, Gainetdinov RRDopamine receptors - IUPHAR Review 13. Br J Pharmacol. 2015 172: 1–23.
  7. Sukhanov I, Espinoza S, Yakovlev DS, Hoener MC, Sotnikova TD, Gainetdinov RRTAAR1-dependent effects of apomorphine in mice. Int J Neuropsychopharmacol. 2014; 17: 1683–93.
  8. Leo D, Mus L, Espinoza S, Hoener MC, Sotnikova TD, Gainetdinov RRTaar1-Mediated Modulation of Presynaptic Dopaminergic Neurotransmission: Role Of D2 Dopamine Autoreceptors. Neuropharmacology. 2014; 81: 283–91.
  9. Siesser WB, Sachs BD, Ramsey AJ, Sotnikova TD, Beaulieu JM, Zhang X, Caron MG, Gainetdinov RRChronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice. ACS Chemical Neuroscience. 2013; 4: 84–8.
  10. Managò F, Espinoza S, Salahpour A, Sotnikova TD, Caron MG, Premont RT, Gainetdinov RRThe role of GRK6 in animal models of Parkinson's Disease and L-DOPA treatment. Sci Rep. 2012; 2: 301.