2013 / 02

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ORIGINAL RESEARCH

The Influence of Perindopril Monotherapy on the Prognostically Meaningful Indicators of Circadian Blood Pressure Monitoring

Orlova NV1, Karseldze ND2, Kuzmenkova LV3, Limonchikova OV3, Mushtaeva TA3, Vasilyeva NE3, Sapozhnikov SA1, Chukaeva II1
About authors

1 Department of Outpatient Therapy No. 2, Medical Faculty,
Pirogov Russian National Research Medical University, Moscow, Russia

2 2Central Clinical Hospital No. 1 of JSC «Russian Railways», Moscow, Russia

3 Municipal Clinical Hospital No. 13, Moscow, Russia

Correspondence should be addressed: Natalia V. Orlova
ul. Ostrovityanova, d. 1, Moscow, Russia, 117997; ur.xednay@513hcarv

Received: 2013-02-25 Accepted: 2013-04-25 Published online: 2017-01-05
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The objective of the study was to assess the effect of perindopril treatment on parameters of circadian blood pressure monitoring. The study included 40 patients with newly diagnosed hypertension I–II degree (40–60 years old). Patients underwent monitoring of blood pressure, pulse wave velocity determination. The perindopril therapy showed the reduction in average circadian blood pressure, pulse blood pressure and variability in systolic blood pressure. It was concluded that perindopril monotherapy is effective in patients with newly diagnosed arterial hypertension I–II degree.

Keywords: hypertension, circadian blood pressure monitoring, blood pressure variability, perindopril

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