The relationships between various heart rate variability indices and score values on the Wein autonomic state scale were studied in 32 students of 18–25 years old. No evident significant correlation was obtained between either of listed indices and score val­ues. This calls into question the use of heart rate variability parameters in the quantitative estimation of systemic autonomic state as well as in identification of autonomic dysfunction and determination of its severity. These results also indicate that the general autonomic dysfunction is not always associated with the overexertion of the adaptation mechanisms.