OPINION

Nuclear medicine imaging in dementia

About authors

1 Department of Radiology, Biomedical Faculty,
Pirogov Russian National Research Medical University, Moscow, Russia

2 Hospital for incurable patients – the Scientific Medical and Rehabilitation Center, Moscow, Russia

3 Department of Radionuclide Imaging,
Central Clinical Hospital of the Russian Academy of Sciences, Moscow, Russia

Correspondence should be addressed: Anton Kondakov
Litovsky bulvar, d. 1a, Moscow, Russia, 117593; moc.liamg@k.a.vokadnok

Received: 2016-08-16 Accepted: 2016-08-21 Published online: 2017-01-05
|
Fig. 1. Brain perfusion SPECT with 99mTc-exametazime, axial sections. (A) Intact brain perfusion. (B) Perfusion pattern typical for Alzheimer’s disease (reduced perfusion in the parietal cortex). (C) Perfusion pattern typical for frontotemporal degeneration (reduced perfusion in the frontal cortex). (D) Perfusion pattern typical for Lewy body dementia and similar to Alzheimer’s; reduced perfusion is observed in the occipital cortex (Dierckx et al. [2])
Fig. 2. SPECT with 123I-ioflupan shows distribution of dopamine transporters. The picture shows axial sections at the striatal level. Left: a section obtained from a healthy volunteer. Right: a section obtained from a patient with Parkinson’s disease (Hauser et al. [15])