2022 / 02

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DOI: 10.24075/brsmu.2022.021

ORIGINAL RESEARCH

Models of mitochondrial dysfunction with inducible expression of Polg pathogenic mutant variant

Kubekina MV1, Kalinina AA2, Korshunova DS1, Bruter AV1, Silaeva YY1
About authors

1 Institute of Gene Biology, Moscow, Russia

2 Blokhin Russian Cancer Research Center, Moscow, Russia

Correspondence should be addressed: Marina V. Kubekina
Beskudnikovsky bulvar, 32, korpus 1, Moscow, 127474, Russia; moc.liamg@ymukyram

About paper

Funding: the study was supported by Russian Foundation for Basic Research, RFBR Project № 19-34-90073.

Author contribution: Kubekina MV — literature analysis, experimental research, data analysis and interpretation, oligo design, manuscript writing; Kalinina AA, Korshunova DS — experimental research; Bruter AV — literature analysis, research planning, data analysis and interpretation; Silaeva YY — literature analysis, research planning, data analysis and interpretation, scientific editing of the manuscript.

Compliance with ethical standards: the study was approved by Ethical Review board at the Institute of Gene Biology (Protocol of 05 December 2021) and carried out in strict compliance with the Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes.

Received: 2022-04-14 Accepted: 2022-04-28 Published online: 2022-04-27
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