ISSN Print 2500–1094
ISSN Online 2542–1204
Bulletin of RSMU
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
T-cadherin gene polymorphism is associated with ischemic heart disease manifestations
About authors
1 Medical Science and Education Centre,Lomonosov Moscow State University, Moscow, Russia
2 Faculty of Fundamental Medicine,Lomonosov Moscow State University, Moscow, Russia
Correspondence should be addressed: Alexandr Balatskiy
Lomonosovsky prospekt, d. 31, korp. 5, Moscow, Russia, 119192; ur.usm.mbf@ykstalab
Received: 2015-12-29
Accepted: 2016-01-20
Published online: 2017-01-05
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Frequency of rs12051272 polymorphism genotypes of CDH13 gene in the studied groups
Table 1. Prevalence of risk factors in the studied groups
For patients with CHD, the age of the disease onset is shown; the median (interquartile range) # is presented; # — p<0.001 when compared with the corresponding figure in the controls.
Table 2. Prevalence of risk factors in the controls and the subgroups of patients
* — for the subgroups of patients, the age at the time of the disease onset is shown; the median (interquartile range) is presented; p1–2 —statistically significant differences between the controls and the subgroup of patients with SEA; p1–3 — statistically significant differences between the controls and the subgroup of patients with MI; p2–3 — statistically significant differences between the subgroups of patients.
Table 3. Frequency of rs12051272 polymorphism genotypes of CDH13 in healthy subjects and patients with stable effort angina without consideration of risk factors
Table 4. Frequency of rs11646213 polymorphism genotypes of CDH13 in healthy subjects and patients with stable effort angina without consideration of risk factors
Table 5. Frequency of rs12051272 polymorphism genotypes of CDH13 in patients with stable effort angina and myocardial infarction with the consideration of all risk factors of interest
