ORIGINAL RESEARCH

Conserved sequences of genes coding for the multidrug resistance pump AcrAB-TolC of Escherichia coli suggest their involvement into permanent cell “cleaning”

Karakozova MV1, Nazarov PA2
About authors

1 Research Centre for Medical Genetics, Moscow

2 Belozersky Institute of Physico-Chemical Biology,
Lomonosov Moscow State University, Moscow

Correspondence should be addressed: Marina Karakozova
Microrayon 1, d.15, kv. 43, Zaraisk, Zaraiski r-n, Moscow region, 140601; moc.liamg@200257kvm

About paper

Acknowledgement: the authors wish to thank students (Dzhafarova T, Mamedova D, Maushev F, Miranian K, Omarova D and Rodionova E) and the Department of Morphology and Pathology of Medical Institute REAVIZ for the provided data, their analysis and discussion.

Received: 2018-02-19 Accepted: 2018-03-30 Published online: 2018-07-06
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Fig. 1. Alignment of AcrA protein sequences for strains K-12 and B against the reference AcrA protein sequence of substrain BW25113
Fig. 2. Alignment of AcrB protein sequences for strains K-12 and B against the reference AcrB protein sequence of substrain BW25113
Fig. 3. Alignment of TolC protein sequences for strains K-12 and B against the reference TolC protein sequence of substrain BW25113
Table 1. Geographic origin of E. coli strains used in this work
Table 2. Accession numbers for the stored protein sequences of acrA, acrB and tolC genes