ISSN Print 2500–1094
ISSN Online 2542–1204
Bulletin of RSMU
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
The study of morphological and functional changes in the thyroid follicles of healthy rats and rats with experimentally induced hypothyroidism following exposure to medium-power laser radiation
About authors
1 Multi-specialty Center of Laser Medicine, Chelyabinsk
2 South Ural State Medical University, Chelyabinsk
Correspondence should be addressed: Irina V. Smelova
Potemkina 14, kv. 65, Chelyabinsk, 454081; ur.liam@vis.larips
Received: 2018-02-15
Accepted: 2018-03-20
Published online: 2018-07-28
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Fig. 1. The intact thyroid gland. Staining: hematoxylin-eosin; 400x magnification
Fig. 2. Hypothyroidism. Staining: hematoxylin-eosin; 400x magnification
Fig. 3. The thyroid of experimental animals on day 7 after irradiation with 112 J/cm2 laser beams. Staining: hematoxylin-eosin; 400x magnification
Fig. 4. The thyroid of experimental animals on day 7 after irradiation with 450 J/cm2 laser beams. Staining: hematoxylin-eosin; 400x magnification
Table 1. Comparative analysis of the epithelium height, diameter and area of follicles in the experimental groups of animals
Note: 1р < 0.05, intact controls compared with animals with untreated induced hypothyroidism; #р < 0.05, irradiated animals compared with intact controls; *р < 0.05, irradiated animals compared with animals with untreated induced hypothyroidism; 0p < 0.05, comparison between the groups of irradiated animals.
Table 2. Comparative analysis of the nucleus/cell ratio and Braun’s index in the experimental groups of animals
Note: 1р < 0.05, intact controls compared with animals with untreated induced hypothyroidism; #р < 0.05, irradiated animals compared with intact controls; *р < 0.05, irradiated animals compared with animals with untreated induced hypothyroidism; 0р < 0.05, comparison between the groups of irradiated animals.
