Bulletin of RSMU

ORIGINAL RESEARCH

Whole-genome sequencing and comparative genomic analysis of Mycobacterium smegmatis mutants resistant to imidazo[1,2-b][1,2,4,5]tetrazines, antituberculosis drug candidates

Maslov DA¹, Bekker OB¹, Shur KV¹, Vatlin AA¹, Korotina AV², Danilenko VN¹

About authors

¹ Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics of RAS, Moscow

² Laboratory of Heterocyclic Compounds, Postovsky Institute of Organic Synthesis, Ekaterinburg

Correspondence should be addressed: Dmitry A. Maslov
Gubkina 3, Moscow, 119333; moc.liamg@kisssam.d

About paper

Funding: the study was supported by the Russian Science Foundation (Grant 17-75-20060).

Acknowledgement: the authors wish to thank Natalya Mikheecheva of the Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics, for her valuable comments and methodological know-how.

Received: 2018-05-30 Accepted: 2018-07-12 Published online: 2018-08-23

Table. Characteristics of the closest homologs of M. tuberculosis proteins with the mutations that presumably confer resistance to antituberculosis drugs

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ORIGINAL RESEARCH Whole-genome sequencing and comparative genomic analysis of Mycobacterium smegmatis mutants resistant to imidazo[1,2-b][1,2,4,5]tetrazines, antituberculosis drug candidates

Maslov DA, Bekker OB, Shur KV, Vatlin AA, Korotina AV, Danilenko VN

Published in "Bulletin of RSMU" 3, 2018

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Vancouver style

Maslov DA, Bekker OB, Shur KV, Vatlin AA, Korotina AV, Danilenko VN. Whole-genome sequencing and comparative genomic analysis of Mycobacterium smegmatis mutants resistant to imidazo[1,2-b][1,2,4,5]tetrazines, antituberculosis drug candidates. Bulletin of RSMU. 2018; (3): 19–22. DOI: 10.24075/brsmu.2018.039

Harvard style

Maslov, D. A., Bekker, O. B., Shur, K. V., Vatlin, A. A., Korotina, A. V. and Danilenko, V. N. (2018), "Whole-genome sequencing and comparative genomic analysis of Mycobacterium smegmatis mutants resistant to imidazo[1,2-b][1,2,4,5]tetrazines, antituberculosis drug candidates", Bulletin of RSMU, no. 3, p. 19–22. DOI: 10.24075/brsmu.2018.039

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2018 / 03

ORIGINAL RESEARCH

Whole-genome sequencing and comparative genomic analysis of Mycobacterium smegmatis mutants resistant to imidazo[1,2-b][1,2,4,5]tetrazines, antituberculosis drug candidates