2019 / 01

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DOI: 10.24075/brsmu.2019.007

ORIGINAL RESEARCH

Detection of Ser450Leu mutation in rpoB gene of Mycobacterium tuberculosis by allele-specific loop-mediated isothermal DNA amplification method

Filipenko ML1, Oscorbin IP1, Khrapov EA1, Shamovskaya DA1, Cherednichenko AG2, Shvartz YaSh2
About authors

1 Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia

2 Novosibirsk Tuberculosis Research Institute, Novosibirsk, Russia

Correspondence should be addressed: Maxim L. Filipenko
Lavrentyev Prospect 8/2, Novosibirsk, 630090; moc.liamg@oknepiliflm

About paper

Funding: the study was done with the financial support of the basic budgetary financing project № VI.62.1.5 «Synthetic biology: development of tools for the genetic material manipulation and creation of promising drugs for therapy and diagnostics» (0309-2018-0003).

Author contribution: Filipenko ML created а general concept of the study, planned experiments, analyzed the results and participated in the writing of this article; Oscorbin IP participated in the writing of this article; Khrapov EA conducted experiments; Shamovskaya DV conducted experiments; Cherednichenko AG analyzed the experiments results; Shvartz YaSh was involved in planning and analyzed the experiments results.

Received: 2018-12-07 Accepted: 2019-02-25 Published online: 2019-03-09
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