2019 / 02

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DOI: 10.24075/brsmu.2019.021

ORIGINAL RESEARCH

Dynamics of hemostasis parameters and endothelial dysfunction markers in patients with thermal injury

Morrison VV1, Bozhedomov AYu2
About authors

1 Saratov State Medical University, Saratov, Russia

2 Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Alexey Yu. Bozhedomov
Ostrovityanova 1, Moscow, 117997; ur.liam@48_oscela

About paper

Author contribution: Morrison VV — design of the experiment, data analysis, manuscript revision; Bozhedomov AYu — data collection and statistical analysis, manuscript draft.

Received: 2018-12-28 Accepted: 2019-03-26 Published online: 2019-04-08
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Table 1. Markers of endothelial dysfunction
Table 2. Hemostasis dynamics in patients with burn injuries, M ± σ
Note: p — the specified and the previous stages of the study are compared; * — the differences between the specified and the previous stages of the study are significant (p < 0.05); pк — the patients compared to the controls at the specified stage of the study; к — the differences between the patients and the controls are significant (p < 0.05).
Table 3. Cytokine dynamics in patients with burn injuries, M ± σ
Note: p — the specified and the previous stages of the study are compared; * — the differences between the specified and the previous stages of the study are significant (p < 0.05); pк — the patients compared to the controls at the specified stage of the study; к — the differences between the patients and the controls are significant (p < 0.05).
Table 4. Dynamics of endothelial dysfunction markers in patients with burn injuries, M ± σ
Note: p — the specified and the previous stages of the study are compared; * — the differences between the specified and the previous stages of the study are significant (p < 0.05); pк — the patients compared to the controls at the specified stage of the study; к — the differences between the patients and the controls are significant (p < 0.05).
Table 5. Differences in the values of blood coagulation parameters in burn patients with normal coagulation and coagulopathy, M ± σ
Note: * — the difference between the two groups is significant (p < 0.05).
Table 6. Differences in the levels of cytokines and endothelial dysfunction markers in burn patients with normal coagulation and coagulopathy, M ± σ
Note: * — the difference between the two groups is significant (p < 0.05).