2019 / 04

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DOI: 10.24075/brsmu.2019.053

ORIGINAL RESEARCH

Effectiveness of intraosseous infiltration of autologous platelet-rich plasma in the area of the bone marrow edema in osteoarthritis of the knee joint

Lychagin AV, Garkavi AV, Islaieh OI, Katunyan PI, Bobrov DS, Yavlieva RH, Tselisheva EYu
About authors

I. M. Sechenov First Moscow State Medical University, Moscow, Russia

Correspondence should be addressed: Osama I. Islaieh
Bolshoi Tishinsky Pereulok 26/15, Moscow, 123557; moc.oohay@osbiaso

About paper

Author contribution: Lychagin AV and Islaieh OI — research planning, literature collection and analysis, data interpretation, draft preparation; Garkavi AV — research planning, data interpretation; Katunyan PI — research planning, draft preparation; Bobrov DS, Yavlieva RH and Tselisheva EY — research planning.

Received: 2019-07-12 Accepted: 2018-07-26 Published online: 2019-08-20
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Fig. 1. Measuring the BME with the help of RadiAnt DICOM Viewer 4.6.9 (64-bit), WORMS. A. BME in the lateral condyle of the femur, size 1.17 cm. B. BME in the medial condyle of the tibia, size 3.14 cm
Fig. 2. Preparation of PRP. 1: Blood collection. 2: Centrifugation. 3: Mixing (10 : 1 ratio). 4: Injection
Fig. 3. EOC-controlled administration of PRP into the BME zone, medial condyle of the femur. EOC image: needle in the femur's medial condyle
Fig. 4. Patients by BME severity, WORMS
Fig. 5. Dynamics of the average values, VAS, WOMAC and KOOS. 17 knee OA patients were injected PRP in the BME zone. Their condition was assessed before injection and 1 and 3 months after treatment.
Table 1. The patients
Table 2. WORMS diagnosis criteria
Table 3. Functional scale, KOOS subscales
Note: * — statistically significant change of the value compared to the initial measurements, p < 0.01.