ISSN Print 2500–1094
ISSN Online 2542–1204
Bulletin of RSMU
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
Lipidome features in patients with different probability of family hypercholesterolemia
About authors
1 Central State Medical Academy of the Department of Presidential Affairs of the Russian Federation, Moscow, Russia
2 City Clinical Hospital № 51, Moscow, Russia
3 Emanuel Institute of Biochemical Physics of the Russian Academy of Sciences, Moscow, Russia
4 Lomonosov Moscow State University, Moscow, Russia
Correspondence should be addressed: Larisa O. Minushkina
Filevsky Boulevard, 36–19, Moscow, 121601; ur.liam@anikhsunim
About paper
Funding: RFBR grant 19-04-00870А Sphingolipidome Analysis of Cardiovascular Diseases’ Markers.
Author contribution: Rogozhina AA — sampling, data acquisition; Minushkina LO — data analysis, text writing; Zateyshchikov DA — planning, data analysis, manuscript writing; Alessenko AV — project manager; Gutner UA, Shupik MA, Maloshitskaya OA and Sokolov SA — sample preparation, laboratory analysis, data analysis; Kurochkin IN — data analysis.
Received: 2019-11-30
Accepted: 2019-12-18
Published online: 2019-12-27
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Fig. 1. Correlation of LDL and blood sphingosine level
Fig. 2. Correlation of HDL and blood sphinganine level
Fig. 3. Correlation of LDL and blood sphingosine level
Table 1. Lipids and sphingolipids level in patiens with different probability of family hyperlipidemia
Note: Kruskal–Wallis test.
Table 2. Blood lipids and sphingolipids in patients with family history and in patients without family history
Note: Mann–Whitney test.
Table 3. Correlation of blood lipids, sphingomyeline and ceramide levels
Note: r — Spearman rank correlation; * — p < 0.005; * * — p < 0.001.
