ISSN Print 2500–1094    ISSN Online 2542–1204
Bulletin of RSMU
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)

Vadim V. NEGREBETSKY

Head of the Department of Medicinal Chemistry and Toxicology,
Head of the Department of Chemistry, Faculty of General Medicine,
Pirogov Russian National Research Medical University (Moscow, Russia)

DSC (chemistry), professor

Areas of expertise:

medicinal, bioorganic, organic and organoelement chemistry, preclinical development of bioactive compounds, nuclear magnetic resonance, dynamic stereochemistry (tautomerism, isomerization, permutational isomerization, cis/trans isomerization)

Special awards and honors:

Academia Europaea Young Scientist Award — Research in dynamic stereochemistry of hypervalent compounds of silicon, germanium and tin (1996)
Russian Federation State Prize for Young Scientists for outstanding contribution to science and technology (1999)

ABOUT SCIENCE:

Significant publications in last 5 years

  1. Negrebetsky VV, Nikolin AA, Kramarova EP, Shipov AG, Baukov YI, Arkhipov DE, et al. N, N-bis-(dimethylfluorosilylmethyl)amides of N-organosulfonylproline and sarcosine: synthesis, structure, stereodynamic behaviour and in silico studies. RSC Advances. 2016; 6: 75315–27. DOI: 10.1039/C6RA14450K.
  2. Bylikin SYu, Korlyukov AA, Shipov AG, Arkhipov DE, Kalashnikova NA, Negrebetsky VV, et al. Regioselective chelation in the reaction of N-trimethylsilyl-N-acetylglycine N',N'-dimethylamide with chloro(chloromethyl)dimethylsilane. Mendeleev Commun. 2015; 25 (2): 114–6.
  3. Prokopenko PG, Shkoporov AN, Petrenko OYu, Efimov BA, Negrebetsky VV, Terentiev AA. Rekombinantnyy N-domen beremennost'-spetsificheskogo glikoproteina iz kletok E-coli: izuchenie spektra poliklonal'nykh antitel. Byulleten' eksperimental'noy biologii i meditsiny. 2015; 160 (7): 88–92. Russian.
  4. Albegova DZ, Pavlova SI, Laptev OS, Negrebetsky VV, Kyagova AA, Kozyr LA, et al. [Influence of modified bioflavonoids upon effector lymphocytes in murine model of contact sensitivity]. Medical Immonology (Russia). 2015; 17 (4): 367–74. Russian.
  5. Prokopenko PG, Petrenko O, Shelepova V, Negrebetsky VV, Mokhosoev IM, Terentiev AA. Ascitic Antigen CA125: Study of Dissociation Forms and its Final – Stem Structure. British Journal of Medicine and Medicinal Research. 2014; 4 (1): 215–24.
  6. Albegova DZ, Pavlova SI, Negrebetsky VV, Кягова А. А., Козырь Л. А. Modifitsirovannyy bioflavanoid supressiruet reaktsiyu kontaktnoy giperchuvstvitel'nosti u myshey. Russian Journal of Immunology. 2014; 17 (1): 11–4. Russian.
  7. Albegova DZ, Pavlova SI, Negrebetsky VV, Kozlov IG. Vliyanie modifitsirovannogo bioflavanoida na proliferatsiyu myshinykh mononuklearov, aktivirovannykh T- i V-kletochnymi mitogenami. Russian Journal of Immunology. 2014; 17 (1): 8–11. Russian.
  8. Ioutsi VA, Markov VYu, Belov NM, Apenova MG, Goryunkov AA, Maksimova ME, Nikitin OM, Kovalev SV, Shevchenko VE, Magdesieva TV, Negrebetsky VV, et al. Pyrrolizidine and cyclobutane bridged double-caged fullerene derivatives. New J Chem. 2013; 37: 804–9.
  9. Nikolin AA, Kramarova EP, Shipov AG, Baukov YuI, Negrebetsky VV, Korlyukov AA, et al. Synthesis, structures, and stereodynamic behaviour of novel pentacoordinate fluorosilanes: fluorosilyl derivatives of proline. Organometallics. 2012; 31 (14): 4988–97.
  10. Kuznetsova OV, Egorochkin AN, Negrebetsky VV, Khamaletdinova NM, Domratcheva-Lvova LG. Ligand-site exchange in intra molecular complexes of silicon: substituent effects. J Physical Organic Chem. 2012; 25 (8): 658–66.