2018 / 02

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DOI: 10.24075/brsmu.2018.022

ORIGINAL RESEARCH

Experimental approaches to the target editing of the CFTR gene using CRISPR-Cas9

Smirnikhina SA1, Anuchina AA1, Kochergin-Nikitsky KS1, Adilgereeva EP1, Yakushina VD1, Lavrov AV1,2
About authors

1 Laboratory of Mutagenesis,
Research Centre for Medical Genetics, Moscow

2 Department of Molecular and Cellular Genetics, Biomedical Faculty,
Pirogov Russian National Research Medical University, Moscow

Correspondence should be addressed: Svetlana Smirnikhina
Moskvorechie 1, Moscow, 115522; moc.liamg@sanihkinrims

About paper

Funding: the section Editing of the CFTR locus was supported by the grant of the Russian Science Foundation (Agreement 17-75-20095), the sections Increasing the expression of guide RNAs and Improving the efficacy of CFTR locus editing were supported by the Russian Academy of Sciences and the state assignment of FASO Russia.

Received: 2018-03-15 Accepted: 2018-03-20 Published online: 2018-07-04
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